top of page
  • drashleighbhanjan2

Unleash the power of photobiomodulation therapy for wound healing

Introduction

Photobiomodulation therapy (PBMT) is a non-invasive, photochemical approach that uses light to induce healing in various medical conditions, including wound healing. In recent years, PBMT has gained attention for its potential benefits in vascular disease, post-operative care, and non-healing wounds.


This blog post will focus on the use of PBMT in wound healing, with an emphasis on the aforementioned areas. We will also compare PBMT to other forms of therapy in terms of speed of recovery, side effects, advantages, and response time, based on the latest clinical and scientific research.



 


Mechanism of action : PBMT


The mechanism of action of PBMT is based on the principle of light-tissue interactions. When light is absorbed by chromophores in cells, it can stimulate various biological processes, including the production of adenosine triphosphate (ATP), which is essential for cellular metabolism and repair. PBMT can also stimulate the production of reactive oxygen species (ROS), which can activate signaling pathways that promote tissue repair and regeneration.


Mechanism of Action in Wound Healing

  • PBM promotes vasodilation and angiogenesis through the actions of nitric oxide, improving blood flow and oxygenation to the wound site.


  • It stimulates fibroblast proliferation and collagen synthesis, enhancing the formation of new tissue and wound closure.


  • PBM modulates the PI3K/AKT/FoxO1 pathway, which plays a crucial role in diabetic wound healing.


  • The therapy can also reduce inflammation and pain, making it beneficial for postoperative care


PBMT can be used to treat a variety of medical conditions, including dermatology, neurobiological diseases, wound healing, pain, inflammation, and sports injuries. PBMT can reduce pain and inflammation for acute and chronic conditions, and it can increase the healing speed of wounds and prevent scar tissue formation. PBMT stimulates fibroblast development in damaged tissue, increasing collagen production and allowing for proper alignment and remodeling of collagen. These processes accelerate wound healing and reduce scar tissue formation following damage from repetitive motion injuries, cuts, scratches, burns, or surgery.





PBMT in Wound Healing

PBMT has been shown to stimulate tissue repair processes, including angiogenesis and cellular mitosis, which contribute to the healing of skin lesions. A scoping review on the effect of blue light on wound healing found that PBMT with blue light can enhance wound closure, reduce inflammation, and promote tissue regeneration.


Additionally, PBMT delivered using low-intensity laser has the potential to improve wound healing and reduce pain, inflammation, edema, and infection.


Vascular Disease

Vascular disease, such as venous leg ulcers, can be challenging to treat. A study on frail elderly patients with municipality home healthcare found that PBMT, as an additional treatment to traditional dressing, can improve wound healing and reduce pain, inflammation, edema, and infection. This suggests that PBMT may be a beneficial adjunctive therapy for patients with vascular disease.


Post-Operative Care

PBMT has been used in post-operative care to enhance wound healing and reduce pain and inflammation. A study on the effects of PBMT on wound healing in an animal model found that PBMT with different wavelengths (658 nm, 830 nm, and 904 nm) can stimulate tissue repair processes, including neovascularization and collagen production, leading to faster wound healing.


This indicates that PBMT may be a valuable tool in post-operative care for patients undergoing surgical procedures.


Non-Healing Wounds

Non-healing wounds, such as diabetic ulcers and pressure ulcers, can be challenging to manage. PBMT has shown promise in promoting the healing of these types of wounds. A review on the use of PBMT in wound care found that PBMT can stimulate fibroblast development, increase collagen production, and accelerate wound healing, leading to reduced scar tissue formation. This suggests that PBMT may be a valuable treatment option for patients with non-healing wounds.


Comparison to Other Forms of Therapy

  • Speed of Recovery: PBMT has been shown to accelerate wound healing processes, leading to faster recovery times. However, the exact speed of recovery may vary depending on the individual patient and the specific wound.


  • Side Effects: PBMT is generally considered safe, with minimal side effects reported. Common side effects include mild redness and warmth at the treatment site, which usually resolve quickly.

.

  • Advantages: PBMT is a non-invasive and painless treatment option that can be easily administered. It does not require the use of drugs or surgery, making it a potentially cost-effective and efficient therapy for wound healing.


  • Response Time: The response time to PBMT may vary depending on the individual patient and the specific wound. Some patients may experience immediate improvements, while others may require multiple treatment sessions to see significant results.


 

Latest Clinical and Scientific Research

  • A scoping review on the effect of blue light on wound healing found that PBMT with blue light can enhance wound closure, reduce inflammation, and promote tissue regeneration.


  • A study on frail elderly patients with municipality home healthcare found that PBMT, as an additional treatment to traditional dressing, can improve wound healing and reduce pain, inflammation, edema, and infection.


  • A study on the effects of PBMT on wound healing in an animal model found that PBMT with different wavelengths (658 nm, 830 nm, and 904 nm) can stimulate tissue repair processes, including neovascularization and collagen production, leading to faster wound healing.


  • A review on the use of PBMT in wound care found that PBMT can stimulate fibroblast development, increase collagen production, and accelerate wound healing, leading to reduced scar tissue formation.

Based on these findings, PBMT shows promise as a valuable tool in wound healing, particularly in the areas of vascular disease, post-operative care, and non-healing wounds.


Further research is needed to fully understand the optimal parameters for PBMT and its long-term effects on wound healing.


References





65 views0 comments

Comments


bottom of page